ZYLEXIS™Parapox Ovis Virus Immunomodulator
Description
An immunomodulator consisting of inactivated (killed) parapox ovis virus, Zylexis aids in the reduction of upper
respiratory disease associated with EHV-1 and EHV-4 that can be expensive to treat, and may compromise the health
of other horses, resulting in lost training or competition time.
Advantages
- Equine herpesvirus (EHV) types 1 & 4 latently infects 80% of all horses
- EHV-1 has been demonstrated to cause respiratory disease including pneumonia, abortion and stillbirth in
pregnant mares, and neurologic symptoms.
- EHV-4 has been demonstrated to cause respiratory disease in young and stressed horses.
- Equine herpesvirus is easily reactivated by common stressors such as environmental changes, training,
competition and trailering.
- Reactivation causes a high viral load that can contribute to sickness, respiratory signs, and sometimes
results in pneumonia.
- These infections can be expensive to treat, may compromise the health of other horses in the barn and may
result in lost training/competition time for valuable show horses.
- Zylexis has been safely and effectively used in horses in Germany since 1998.
- Safe for use in healthy horses including foals four months of age and older.
Indications
For use in healthy horses four months of age or older as an aid in reducing upper respiratory disease caused by equine
herpesvirus types 1 and 4.
Precautions
- Do not administer within 21 days before slaughter.
- For use in horses only. Do not use in other animal species.
- Keep this and all drugs out of reach of children.
- In case of anaphylaxis, adminster epinephrine or equivalent.
Safety
Zylexis is safe for use in healthy horses, including foals four months of age and older.
Dosage and Administration
Aseptically rehydrate the freeze-dried component with the sterile diluent provided. Shake well and administer 2 mL
intramuscularly. Repeat the 2-mL dose on days 2 and 9 following the initial dose. Retreatment is recommended during
subsequent disease episodes or prior to stress-inducing situations.
Recommended Storage
Store at 2° - 8° C. Do not freeze. Use entire contents when first opened. Sterilized syringes and
needles should be used to administer this immunomodulator.
Packaging
5 x 1 dose vials of immunomodulator. Rehydrate to 2 mL.
5 x 2 mL vials of sterile diluent.
Product Information
Material Safety Data Sheet
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