Description

• VANGUARD^® PLUS 5 contains attenuated strains of canine distemper (CD) virus, canine adenovirus-2 (CAV-2), canine parvovirus (CPV), and canine parainfluenza (CPI) virus propagated on an established canine cell line.



• The freeze-dried components are rehydrated with a sterile diluent.



• The PLUS in VANGUARD PLUS vaccines refers to the high-titer, low-passage canine parvovirus (CPV) component, which provides added immunogenicity that can override appreciable levels of maternal CPV antibodies in puppies 6 weeks of age or older.



• All VANGUARD PLUS vaccines contain an attenuated strain of canine adenovirus-2 (CAV-2), which protects against CAV-2 respiratory disease and against infectious canine hepatitis (ICH) caused by the closely related canine adenovirus-1 (CAV-1). The CAV-2 component provides this dual protection without causing postvaccination side effects (uveitis and corneal opacity) sometimes associated with conventional CAV-1 vaccines.

• Vaccination of healthy dogs as an aid in preventing disease caused by CD, ICH caused by CAV-1, CAV-2 respiratory disease, CPV enteritis, and respiratory disease caused by CPI virus.



• Vaccination of healthy dogs 6 weeks of age or older.

• The CAV-2 component in VANGUARD PLUS vaccines cross-immunizes against CAV-1 to protect dogs against ICH without producing postvaccination side effects, including uveitis and corneal opacity, sometimes attributed to CAV-1 vaccines.



• Customer-friendly packaging using recycled materials includes peel-off labels to make record-keeping faster and more accurate, a color-coded organizing system, and an easy-open safety band.

• General directions: Vaccination of healthy dogs is recommended. Aseptically rehydrate the freeze-dried vaccine with the liquid component provided. Shake well, and administer a 1 mL dose subcutaneously or intramuscularly.



• Primary vaccination: Healthy dogs 6 weeks of age or older should receive 3 doses, each given 3 weeks apart.



• Revaccination: Annual revaccination with a single dose is recommended.

• Store at 2°–7° C. Prolonged exposure to higher temperature and/or direct sunlight may adversely affect potency. Do not freeze. Use entire contents when first opened. Sterilized syringes and needles should be used. Burn containers and all unused contents.



• As with many vaccines, anaphylaxis may occur after use. Initial antidote of epinephrine is recommended and should be followed with appropriate supportive therapy. This product has been shown to be efficacious in healthy animals. A protective immune response may not develop if animals are incubating an infectious disease, are malnourished or parasitized, are stressed due to shipment or environmental conditions, are otherwise immunocompromised, or if the vaccine is not administered according to label directions.



• For use in dogs only.



• Vaccination of pregnant bitches should be avoided.



• For veterinary use only.