Long-Lasting Itch Relief

DEPO-MEDROL^® (methylprednisolone acetate) has the power to quickly relieve inflammation and seasonal itching, with minimal side effects. One injection provides a slow, consistent release of effective anti-inflammatory medication providing sustained relief. The acetate formulation maintains gradually declining drug levels to allay symptoms for weeks. DEPO-MEDROL improves anti-inflammatory action by 25% compared with prednisolone, with even less tendency to induce sodium and water retention. DEPO-MEDROL offers more anti-inflammatory action than any other medication in its class and with an unsurpassed side-effect profile.

Indications

Allergic Conditions: Relieves itching and inflammation of allergic dermatitis, acute moist dermatitis, dry eczema, urticaria, bronchial sensitivities, and otitis externa in dogs.

Musculoskeletal Conditions: Useful in treating traumatic arthritis, osteoarthritis and generalized arthritic conditions in dogs.

Overwhelming Infections with Severe Toxicity: In dogs that have a strong possibility of dying from overwhelmingly severe infections that can be cured by antibiotic therapy (such as critical pneumonia or pyometritis), DEPO-MEDROL may be lifesaving. DEPO-MEDROL inhibits the inflammatory reaction, which may be lethal by itself. DEPO-MEDROL prevents vascular collapse and preserves the integrity of the blood vessels.

Other Conditions: Useful when it is desirable to reduce inflammation, vascularization, fibroblastic infiltration and scar tissue. Indicated for snakebite due to its antitoxemic, anti-inflammatory and antishock activity. Particularly effective in reducing swelling and preventing sloughing.

Key Features

Safe and Effective:

• By achieving equal anti-inflammatory effect with lower doses, the active ingredient in DEPO-MEDROL helps minimize polyuria and polydypsia.
  
  
• The small particle size of the active ingredient means the product stays in suspension longer, distributes more evenly in tissues for a more consistent response.

• Concentration in blood peaks soon after administration and then gradually declines over a 2- to 3-week period. This eliminates the need for declining dosage schedules, often required when using daily tablet therapy.
  
  
• A single injection is easy for pets and their owners. Clients don't have to worry about pilling; pets don't have to deal with the stress.

• In-clinic administration eliminates client compliance issues.

• 5-mL vials of 40 mg/mL
  
  
• 10-mL vials of 20 mg/mL
  
  
• 20-mL vials of 20 mg/mL

As with other cortiocosteroids, this product is contraindicated in animals with tuberculosis, hyperadrenocorticism and peptic ulcers. Use may induce parturition when administered during the last trimester of pregnancy, may be associated with other birth-related complications and may result in congenital birth defects.

Suppression of inflammation may mask the signs of infection. Patients should be watched for evidence of concurrent infection.

For use in animals only.

Not for use in humans.

Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Product Information
Material Safety Data Sheet

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