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CLAVAMOX® DROPS
(amoxicillin trihydrate/clavulanate potassium)
Drops

Description

  • Canine broad-spectrum antibiotic in oral dosage form solution.


  • Combines broad-spectrum antibiotic activity of amoxicillin with unique β-lactamase inhibiting effect of clavulanic acid, which extends the antibacterial spectrum to β-lactamase-producing and non-β-lactamase-producing organisms.


  • Has activity against many gram-positive and gram-negative aerobic and anaerobic microorganisms.
Approved Uses

CLAVAMOX® (amoxicillin trihydrate/clavulanate potassium) DROPS are approved for treatment of the following canine infections:
  • Skin and soft-tissue infections such as wounds, abscesses, cellulitis, and superficial/juvenile and deep pyoderma due to susceptible strains of the following organisms: β-lactamase-producing Staphylococcus aureus, non-β-lactamase-producing Staphylococcus aureus, Staphylococcus spp., Streptococcus spp. and E. coli.


  • Periodontal infections due to susceptible strains of both aerobic and anaerobic bacteria.
Key Features

  • Overcomes β-lactamase resistance by irreversibly binding β-lactamase to clavulanic acid component, allowing the amoxicillin component to exert antibacterial effect.


  • Unique, dual mode of action minimizes resistance to CLAVAMOX despite extensive real-world clinical use.


  • Effective for first-time skin infections and persistent pyodermas.


  • Effective in treating mixed periodontal infections involving aerobic and anaerobic bacteria.


  • Wide margin of safety, with no contraindications other than allergic history. (See precautions.)


  • Offers duration of therapy of up to 30 days.
Packaging

15-mL bottles containing 50 mg of amoxicillin/12.5 mg of clavulanic acid per mL.

Dosage and Administration

The recommended dosage is 6.25 mg/lb (1 mL/10 lb) of body weight twice a day. Skin and soft-tissue infections such as abscesses, cellulitis, wounds, superficial/juvenile pyoderma, and periodontal infections should be treated for 5 to 7 days or for 48 hours after all symptoms have subsided. If no response is seen after 5 days of treatment, therapy should be discontinued and the case re-evaluated. Deep pyoderma may require treatment for 21 days. The maximum duration of treatment should not exceed 30 days.

Precautions

  • Use is contraindicated in animals with a history of allergic reaction to any of the penicillins or cephalosporins.


  • CLAVAMOX contains a semisynthetic penicillin (amoxicillin) and has the potential for producing allergic reactions. If an allergic reaction occurs, administer epinephrine and/or steroids.


  • Safety in pregnant or breeding animals has not been determined.


  • Store in a dry, cool place at temperatures not above 25° C (77° F).


  • Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Product Information
Material Safety Data Sheet

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The product information provided in this site is intended only for residents of the United States. The products discussed herein may have different product labeling in different countries.

The health information contained herein is provided for educational purposes only and is not intended to replace discussions with a healthcare provider. All decisions regarding patient care must be made with a healthcare provider, considering the unique characteristics of the patient.