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CLAVAMOX® DROPS
(amoxicillin trihydrate, clavulanate potassium)
Drops

Description

  • Feline broad-spectrum antibiotic in two oral dosage forms: oral solution and tablets.


  • Combines broad-spectrum antibiotic activity of amoxicillin with unique β-lactamase inhibiting effect of clavulanic acid, which extends the antibacterial spectrum to β-lactamase-producing and non-β-lactamase-producing organisms.


  • Has activity against many gram-positive and gram-negative aerobic and anaerobic microorganisms.
Approved Uses

CLAVAMOX® DROPS are approved for treatment of the following feline infections:
  • Skin and soft-tissue infections such as wounds, abscesses, and cellulitis/dermatitis due to susceptible strains of the following organisms: β-lactamase-producing Staphylococcus aureus, non-β-lactamase-producing Staphylococcus aureus, Staphylococcus spp, Streptococcus spp, E. coli, Pasteurella multocida and Pasteurella spp


  • Urinary tract infections (cystitis) due to susceptible strains of E. coli
Key Features

  • Overcomes β-lactamase resistance by irreversibly binding β-lactamase to clavulanic acid component, allowing amoxicillin component to exert antibacterial effect.


  • Unique, dual mode of action minimizes resistance to CLAVAMOX despite extensive real-world clinical use.


  • Effective for first-time skin infections and persistent pyodermas.


  • Effective in treating mixed periodontal infections involving aerobic and anaerobic bacteria.


  • Wide margin of safety, with no contraindications other than allergic history.


  • Offers duration of therapy of up to 30 days.
Packaging

15-mL bottles containing 50 mg of amoxicillin/12.5 mg of clavulanic acid per mL.

Dosage and Administration

  • The recommended dosage is 62.5 mg (1 mL) twice a day. Skin and soft-tissue infections such as abscesses and cellulitis/dermatitis should be treated for 5 to 7 days or 48 hours after all symptoms have subsided, not to exceed 30 days. If no response is seen after 3 days of treatment, therapy should be discontinued and the case re-evaluated. Urinary tract infections may require treatment for 10 to 14 days or longer. The maximum duration of treatment should not exceed 30 days.


  • To reconstitute, add 14 mL of water to the 15-mL bottle and shake vigorously. Each mL of suspension will contain 50 mg of amoxicillin and 12.5 mg of clavulanic acid. Any unused portion of the reconstituted suspension should be discarded after 10 days. Refrigeration of the reconstituted suspension is required.
Precautions

  • Use is contraindicated in animals with a history of an allergic reaction to any of the penicillins or cephalosporins.


  • CLAVAMOX contains a semi-synthetic penicillin (amoxicillin) and has the potential for producing allergic reactions. If an allergic reaction occurs, administer epinephrine and/or steroids.


  • Safety in pregnant or breeding animals has not been determined.


  • Store in a dry, cool place at temperatures not above 25° C (77° F).


  • Federal law restricts use by or on the order of a licensed veterinarian.

Product Information
Material Safety Data Sheet

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The product information provided in this site is intended only for residents of the United States. The products discussed herein may have different product labeling in different countries.

The health information contained herein is provided for educational purposes only and is not intended to replace discussions with a healthcare provider. All decisions regarding patient care must be made with a healthcare provider, considering the unique characteristics of the patient.